Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322261 | 0.93 | HRH3 (0.36) | TP53SMN1; SMN2FPR3FPR2GBA1 | |
| SCHEMBL9321464 | 0.91 | KCNA3 (0.40) | TP53SMN1; SMN2KCNA3SPHK1GBA1 | |
| SCHEMBL9323677 | 0.85 | SMN1; SMN2 (0.39) | TP53SMN1; SMN2FPR3FPR2USP2 | |
| SCHEMBL9322707 | 0.82 | FPR3 (0.40) | TP53SMN1; SMN2FPR3FPR2 | |
| SCHEMBL12514044 | 0.82 | SMN1; SMN2 (0.40) | TP53SMN1; SMN2KCNA3SPHK1 | |
| SCHEMBL9321412 | 0.82 | SMN1; SMN2 (0.48) | TP53SMN1; SMN2FPR3FPR2 | |
| SCHEMBL9322316 | 0.81 | CARM1 (0.41) | TP53SMN1; SMN2FPR3FPR2SIGMAR1 | |
| SCHEMBL9322401 | 0.81 | GAA (0.40) | TP53SMN1; SMN2FPR3FPR2 | |
| SCHEMBL9322327 | 0.81 | HRH3 (0.42) | TP53SMN1; SMN2FPR3FPR2SIGMAR1 | |
| SCHEMBL9321403 | 0.81 | HRH3 (0.42) | TP53SMN1; SMN2FPR3FPR2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |