Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.38 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.38 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321412 | 0.92 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1HSD17B10POLBLMNA | |
| SCHEMBL9322356 | 0.85 | BCHE (0.47) | SMN1; SMN2ALDH1A1HSD17B10LMNAKDM4E | |
| SCHEMBL3937676 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1GAALMNAL3MBTL1 | |
| SCHEMBL9321464 | 0.81 | KCNA3 (0.40) | SMN1; SMN2ALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL9324616 | 0.79 | GAA (0.46) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9322401 | 0.77 | GAA (0.40) | SMN1; SMN2ALDH1A1HSD17B10GAAGNAI3 | |
| SCHEMBL9322225 | 0.76 | THRA (0.40) | SMN1; SMN2ALDH1A1HSD17B10GAAGNAI3 | |
| SCHEMBL9323677 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2HSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL9322436 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2ALDH1A1GAALMNAL3MBTL1 | |
| SCHEMBL9324758 | 0.74 | LTA4H (0.42) | SMN1; SMN2ALDH1A1HSD17B10GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |