Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323550 | 0.93 | TP53 (0.39) | TP53SMN1; SMN2GBA1FPR3FPR2 | |
| SCHEMBL12309907 | 0.84 | PDCD1 (0.42) | HRH3PDCD1CD274TP53SMN1; SMN2 | |
| SCHEMBL12309178 | 0.84 | PDCD1 (0.42) | HRH3PDCD1CD274TP53SMN1; SMN2 | |
| SCHEMBL9321464 | 0.83 | KCNA3 (0.40) | TP53SMN1; SMN2GBA1 | |
| SCHEMBL26012973 | 0.81 | GBA1 (0.47) | HRH3PDCD1CD274HRH2HRH1 | |
| SCHEMBL19958437 | 0.81 | GBA1 (0.47) | HRH3PDCD1CD274HRH2HRH1 | |
| SCHEMBL17574694 | 0.81 | GBA1 (0.47) | HRH3PDCD1CD274HRH2HRH1 | |
| SCHEMBL9323677 | 0.81 | SMN1; SMN2 (0.39) | HRH3TP53SMN1; SMN2FPR3FPR2 | |
| SCHEMBL9322356 | 0.80 | BCHE (0.47) | TP53SMN1; SMN2 | |
| SCHEMBL24428913 | 0.79 | GBA1 (0.42) | HRH3PDCD1CD274HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |