Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324570 | 0.86 | NPSR1 (0.41) | MAPK14NPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL4587677 | 0.81 | NPC1 (0.45) | LMNANPSR1MT-CO2ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL27958928 | 0.79 | LMNA (0.46) | LMNANPSR1MT-CO2CYP3A4ALDH1A1 | |
| SCHEMBL6037567 | 0.79 | KDR (0.42) | GAALMNANPSR1ALDH1A1POLB | |
| SCHEMBL337227 | 0.77 | NPC1 (0.42) | LMNANPSR1MT-CO2MEN1KMT2A | |
| SCHEMBL29504742 | 0.77 | NPC1 (0.42) | LMNANPSR1MT-CO2MEN1KMT2A | |
| SCHEMBL4588620 | 0.76 | HTR3E (0.47) | LMNAMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL6037557 | 0.75 | BAZ2B (0.40) | GAALMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL8656698 | 0.75 | MAPT (0.30) | MEN1KMT2ATDP1MAPT | |
| SCHEMBL28834471 | 0.74 | MEN1 (0.44) | LMNAMT-CO2MEN1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0236022-B1 | Lubricating composition for plastic working and articles worked by using the same | HITACHI LTD (JP) | 1994-02-09 | — | — | EP | disclosed |
| EP-0236022-A2 | Lubricating composition for plastic working and articles worked by using the same | HITACHI, LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |