Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 7/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.34 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28495868 | 0.82 | MEN1 (0.47) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL12056655 | 0.77 | EGFR (0.46) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL9323490 | 0.77 | LMNA (0.50) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL659228 | 0.75 | CNR2 (0.46) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL7150414 | 0.74 | EGFR (0.47) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL17531379 | 0.74 | CNR2 (0.43) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL1305857 | 0.72 | CNR2 (0.44) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL2139359 | 0.72 | CNR2 (0.44) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL2138070 | 0.72 | CNR2 (0.44) | MEN1KMT2AHTTSMN1; SMN2CNR2 | |
| SCHEMBL5195399 | 0.71 | GRK6 (0.49) | MEN1KMT2AHTTSMN1; SMN2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0402667-B1 | Diarylimidazoles | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-02 | — | — | EP | disclosed |
| US-5274095-A | A 4-(4-(julolid-9-yl)imidazol-2-yl-2,6-ditert-butyl-phenol derivative | BOEHRINGER MANNHEIM GMBH (DE) | 1993-12-28 | — | — | US | disclosed |
| US-5162200-A | METHOD FOR DETERMINATION OF A PEROXIDATE-ACTING SUBSTANCE WITH A DIARYLIMIDAZOLE COMPOUND | BOEHRINGER MANNEHEIM GMBH (DE) | 1992-11-10 | — | — | US | disclosed |
| EP-0402667-A1 | Diarylimidazoles | Roche Diagnostics GmbH (DE) | 1990-12-19 | — | — | EP | disclosed |