SCHEMBL659228

SCHEMBL659228

CCCN(CCC)c1ccc(C(c2ccc(N(CCC)CCC)cc2)c2ccc(N(CCC)CCC)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.46
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MEN1 O00255 1/20 0.43
HTT P42858 1/20 0.43
GRK6 P43250 1/20 0.41
EGFR P00533 1/20 0.40
ERBB2 P04626 1/20 0.40
SLC2A1 P11166 1/20 0.39
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 3/20 0.38
NPSR1 Q6W5P4 2/20 0.38
CYP3A4 P08684 2/20 0.37
MAPK1 P28482 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
PSMD14 O00487 1/20 0.37
RECQL P46063 1/20 0.37
GFER P55789 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5195399 0.94 GRK6 (0.49) CNR2KMT2ASMN1; SMN2MEN1HTT
SCHEMBL655214 0.87 CNR2 (0.49) CNR2GRK6EGFRERBB2SLC2A1
SCHEMBL7150414 0.85 EGFR (0.47) CNR2KMT2ASMN1; SMN2MEN1HTT
SCHEMBL16689642 0.85 SLC2A1 (0.49) CNR2GRK6SLC2A1TSHRALDH1A1
SCHEMBL12056655 0.84 EGFR (0.46) CNR2KMT2ASMN1; SMN2MEN1HTT
SCHEMBL3901022 0.84 CNR2 (0.44) CNR2GRK6EGFRERBB2
SCHEMBL80942 0.84 CNR2 (0.44) CNR2GRK6EGFRERBB2
SCHEMBL2139359 0.83 CNR2 (0.44) CNR2KMT2ASMN1; SMN2MEN1HTT
SCHEMBL2138070 0.83 CNR2 (0.44) CNR2KMT2ASMN1; SMN2MEN1HTT
SCHEMBL1305857 0.83 CNR2 (0.44) CNR2KMT2ASMN1; SMN2MEN1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7501172-B2 Integrated recording and labeling with optical recording device HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2009-03-10 US claimed
US-20070225276-A1 7-Phenylsulfonyl-Tetrahydro-3-Benzazepine Dervatives as Antipsychotic Agents GLAXO GROUP LIMITED (GB) 2007-09-27 US claimed
US-7172991-B2 Integrated CD/DVD recording and labeling HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2007-02-06 US claimed
US-20060262178-A1 Integrated recording and labeling with optical recording device ANDERSON DARYL E 2006-11-23 US claimed
EP-1687005-A1 7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS GLAXO GROUP LIMITED (GB) 2006-08-09 EP claimed
WO-2005051398-A1 7-PHENYLSULFONYL-TETRAHYDRO-3-BENZAZEPINE DERIVATIVES AS ANTIPSYCHOTIC AGENTS GLAXO GROUP LIMITED (GB) 2005-06-09 WO claimed
US-20050080260-A1 Preparation of prodrugs for selective drug delivery LUMINIDE 2005-04-14 US claimed
US-20030108708-A1 Integrated CD/DVD recording and labeling HEWLETT-PACKARD DEVELOPMENT COMPANY L.P. 2003-06-12 US claimed
US-20220372312-A1 MARKING COMPOSITIONS SANFORD L.P. 2022-11-24 US disclosed
EP-4092089-A1 MARKING COMPOSITIONS Sanford, L.P. (US) 2022-11-23 EP disclosed
EP-2380567-B1 MELANIN PRODUCTION INHIBITOR POLA CHEM IND INC (JP) 2019-01-16 EP disclosed
US-9797885-B2 Methods and articles for the detection of exposure to polyhydroxyaromatic skin irritants SeeLeaf Inc. (US) 2017-10-24 US disclosed
US-9611409-B2 Color developing colorless primer OATEY CO. (US) 2017-04-04 US disclosed
US-20160327546-A1 METHODS AND ARTICLES FOR THE DETECTION OF EXPOSURE TO POLYHYDROXYAROMATIC SKIN IRRITANTS SEELEAF INC 2016-11-10 US disclosed
EP-0311926-A2 Photopolymerisable composition MORTON INTERNATIONAL, INC. (US) 1989-04-19 EP disclosed
US-4271251-A LEUCO DYE, PHOTOOXIDIZER, 2,4-DIHYDROXY-BENZALDOXIME FUJI PHOTO FILM CO., LTD. (JP) 1981-06-02 US disclosed
US-4139390-A Presensitized printing plate having a print-out image EASTMAN KODAK COMPANY (US) 1979-02-13 US disclosed
US-4119466-A MEROCYANINE DYES EASTMAN KODAK COMPANY (US) 1978-10-10 US disclosed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US disclosed
US-4062686-A MEROCYANINE BENZOTHIAZOLINES OR BENZOSELENAZOLINES EASTMAN KODAK COMPANY (US) 1977-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080260-A1 Preparation of prodrugs for selective drug delivery APEH, PAH, ALAD CNR2 2971/4885KMT2A 3377/4885SMN1; SMN2 3228/4885
US-20070225276-A1 7-Phenylsulfonyl-Tetrahydro-3-Benzazepine Dervatives as Antipsychotic Agents HTR4, DRD4, SLC6A3 CNR2 40/4885KMT2A 662/4885SMN1; SMN2 2075/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.