Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1305857 | 1.00 | CNR2 (0.44) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL2138070 | 1.00 | CNR2 (0.44) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL659228 | 0.83 | CNR2 (0.46) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL2140323 | 0.83 | ALDH1A1 (0.58) | CNR2ALDH1A1TSHRL3MBTL1PSMD14 | |
| SCHEMBL2139215 | 0.83 | ALDH1A1 (0.58) | CNR2ALDH1A1TSHRL3MBTL1PSMD14 | |
| SCHEMBL1305288 | 0.83 | ALDH1A1 (0.58) | CNR2ALDH1A1TSHRL3MBTL1PSMD14 | |
| SCHEMBL7150414 | 0.82 | EGFR (0.47) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL12056655 | 0.81 | EGFR (0.46) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL28495868 | 0.78 | MEN1 (0.47) | CNR2MEN1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL5195399 | 0.78 | GRK6 (0.49) | CNR2MEN1HTTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8586498-B2 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-11-19 | — | — | US | disclosed |
| US-8497400-B2 | Homogeneous asymmetric hydrogenation process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-30 | — | — | US | disclosed |
| US-8481791-B2 | Homogeneous asymmetric hydrogenation process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2013-07-09 | — | — | US | disclosed |
| US-20110065929-A1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-17 | — | — | US | disclosed |
| US-7902110-B2 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-03-08 | — | — | US | disclosed |
| US-7754889-B2 | 1,2-di(4-N,N-dimethylaminophenyl)ethylene-1,2-diamine catalyst complex for asymmetric synthesis; for producing an optically active alcohol using the catalyst to asymmetrically reduce a ketone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-07-13 | — | — | US | disclosed |
| US-20100168440-A1 | Homogeneous Asymmetric Hydrogenation Process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20100137615-A1 | Homogeneous Asymmetric Hydrogenation Process | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2010-06-03 | — | — | US | disclosed |
| EP-2095875-A1 | Homogeneous asymmetric hydrogenation catalyst | Takasago International Corporation (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-20090203927-A1 | Homogeneous asymmetric hydrogenation catalyst | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-1911516-A1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2008-04-16 | — | — | EP | disclosed |
| US-20070149831-A1 | 1,2-di(4-N,N-dimethylaminophenyl)ethylene-1,2-diamine catalyst complex for asymmetric synthesis; for producing an optically active alcohol using the catalyst to asymmetrically reduce a ketone | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137615-A1 | Homogeneous Asymmetric Hydrogenation Process | HDHD5, HHAT, HVCN1 | CNR2 2039/4885MEN1 3092/4885HTT 521/4885 |
| US-20090203927-A1 | Homogeneous asymmetric hydrogenation catalyst | HDHD5, HHAT, HACL2 | CNR2 1863/4885MEN1 2776/4885HTT 487/4885 |
| US-20110065929-A1 | HOMOGENEOUS ASYMMETRIC HYDROGENATION CATALYST | HDHD5, HHAT, HACL2 | CNR2 1863/4885MEN1 2776/4885HTT 487/4885 |
| US-20070149831-A1 | 1,2-di(4-N,N-dimethylaminophenyl)ethylene-1,2-diamine catalyst complex for asymmetric synthesis; for producing an optically active alcohol using the catalyst to asymmetrically reduce a ketone | ADH1C, ADH1A, ADH5 | CNR2 645/4885MEN1 2432/4885HTT 4599/4885 |
| US-20100168440-A1 | Homogeneous Asymmetric Hydrogenation Process | HDHD5, HHAT, HVCN1 | CNR2 2039/4885MEN1 3092/4885HTT 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.