Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229570 | 0.95 | THRA (0.50) | THRATHRBMAPTLMNAALDH1A1 | |
| SCHEMBL2249192 | 0.88 | ESR1 (0.52) | THRATHRBMAPTLMNAALDH1A1 | |
| SCHEMBL6933094 | 0.88 | ESR1 (0.52) | THRATHRBMAPTLMNAALDH1A1 | |
| SCHEMBL9322138 | 0.86 | THRA (0.54) | THRATHRBMAPTLMNAALDH1A1 | |
| SCHEMBL22502160 | 0.86 | MAPT (0.45) | THRATHRBMAPTLMNAALDH1A1 | |
| SCHEMBL20631194 | 0.84 | HTT (0.51) | THRATHRBLMNAESR1PLA2G4B | |
| SCHEMBL5903503 | 0.83 | ALDH1A1 (0.71) | THRATHRBMAPTLMNAALDH1A1 | |
| SCHEMBL26651124 | 0.83 | HTT (0.53) | THRATHRBMAPTLMNAESR1 | |
| SCHEMBL16067478 | 0.82 | ALDH1A1 (0.69) | THRATHRBMAPTLMNAALDH1A1 | |
| SCHEMBL10074635 | 0.82 | HTT (0.52) | THRATHRBMAPTLMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001650-B1 | ACYLACETANILIDE COMPOUNDS AND THEIR USE AS YELLOW FORMING COLOUR COUPLERS FOR SILVER HALIDE PHOTOGRAPHY | AGFA-GEVAERT N.V. (BE) | 1982-07-28 | — | — | EP | disclosed |
| US-4201584-A | Silver halide elements containing yellow forming color couplers for silver halide photography | AGFA-GEVAERT N.V. (BE) | 1980-05-06 | — | — | US | disclosed |
| EP-0001650-A1 | Acylacetanilide compounds and their use as yellow forming colour couplers for silver halide photography | AGFA-GEVAERT N.V. (BE) | 1979-05-02 | — | — | EP | disclosed |