SCHEMBL9322221

SCHEMBL9322221

O=Cc1c(F)c(F)c(Br)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25259657 0.86
SCHEMBL6879181 0.86 VCP (0.31)
SCHEMBL809345 0.84 VCP (0.33)
SCHEMBL14876922 0.81
SCHEMBL419449 0.81 VCP (0.38)
SCHEMBL2238115 0.79
SCHEMBL1808857 0.78 VCP (0.36)
SCHEMBL27632776 0.78 ERN1 (0.36) ERN1
SCHEMBL25863028 0.78
SCHEMBL22042201 0.77 MEN1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12312348-B2 RET inhibitors, pharmaceutical compositions and uses thereof SUNSHINE LAKE PHARMA CO., LTD. (CN) 2025-05-27 US disclosed
CN-113906577-B Organic light emitting device 株式会社LG化学 2025-02-21 CN disclosed
EP-4181224-B1 ORGANIC LIGHT-EMITTING DEVICE LG CHEMICAL LTD (KR) 2025-01-01 EP disclosed
CN-111285874-B RET inhibitor, pharmaceutical composition thereof and application thereof 广东东阳光药业股份有限公司 2024-08-09 CN disclosed
US-11997921-B2 Organic light emitting device LG CHEM, LTD. (KR) 2024-05-28 US disclosed
CN-114171691-B Organic light emitting device 株式会社LG化学 2024-03-26 CN disclosed
CN-113795477-B Novel compound and organic light emitting device comprising the same 株式会社LG化学 2023-12-12 CN disclosed
CN-117164446-A Photocatalytic oxidative degradation method for polymer containing styrene structural unit 大连理工大学 2023-12-05 CN disclosed
US-20230309369-A1 Organic Light-Emitting Device LG CHEM, LTD. (KR) 2023-09-28 US disclosed
US-20230309369-A1 Organic Light-Emitting Device LG CHEM, LTD. (KR) 2023-09-28 US disclosed
EP-3524646-A1 IONIC COMPOUND, COATING COMPOSITION COMPRISING SAME, AND ORGANIC LIGHT-EMITTING DIODE LG Chem, Ltd. (KR) 2019-08-14 EP disclosed
EP-3511382-A1 ORGANIC LIGHT-EMITTING DIODE LG Chem, Ltd. (KR) 2019-07-17 EP disclosed
EP-0271240-B1 Fluorobenzyl esters ZENECA LTD (GB) 1994-01-19 EP disclosed
US-5132469-A Insecticides, Miticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-07-21 US disclosed
US-5017606-A Insecticides, miticides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-05-21 US disclosed
EP-0196156-B1 FLUOROBENZYL ESTERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-02-07 EP disclosed
US-4762835-A INSECTICIDES, MITICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-08-09 US disclosed
EP-0271240-A2 Fluorobenzyl esters ZENECA LIMITED (GB) 1988-06-15 EP disclosed
EP-0227415-A2 Pyrimidine derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-07-01 EP disclosed
EP-0196156-A1 Fluorobenzyl esters IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-10-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12312348-B2 RET inhibitors, pharmaceutical compositions and uses thereof RET, SLC10A2, REL ERN1 3247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.