Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | UGCG | Q16739 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9448997 | 0.99 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449174 | 0.99 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449129 | 0.98 | RAB9A (0.44) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Methoxymethane SCHEMBL9448899 | 0.95 | LMNA (0.46) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Ether SCHEMBL9449179 | 0.92 | LMNA (0.43) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL9449053 | 0.91 | RAB9A (0.48) | UGCGRAB9A | |
| Hydrochloric Acid SCHEMBL9449006 | 0.90 | RAB9A (0.49) | UGCGRAB9AHRH3 | |
| SCHEMBL9879600 | 0.89 | TP53 (0.47) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL10764616 | 0.89 | TP53 (0.47) | TP53CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL10891161 | 0.89 | AOC3 (0.52) | TP53CYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250546-A | Administering as therapy for spastic paralysis; glutamic acid blocking agent; agricultural chemicals | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-10-05 | — | — | US | claimed |
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5250546-A | Administering as therapy for spastic paralysis; glutamic acid blocking agent; agricultural chemicals | NIPPON CHEMIPHAR CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0177245-B1 | AMINO-ALCOHOL DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-04-10 | — | — | EP | disclosed |
| EP-0235942-A1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |