Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RGS4 | P49798 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 4/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643034 | 0.78 | MAPT (0.47) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL28660965 | 0.73 | MAPT (0.49) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL9324699 | 0.71 | MAPT (0.44) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL9322143 | 0.68 | ALDH1A1 (0.41) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL9323705 | 0.65 | ALDH1A1 (0.38) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL1408501 | 0.64 | BACE1 (0.64) | MAPTALDH1A1NPSR1HPGDLMNA | |
| SCHEMBL152254 | 0.64 | MAPT (0.55) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL10396897 | 0.64 | MAPT (0.50) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL152219 | 0.63 | MAPT (0.53) | MAPTALDH1A1NPSR1GAACCR6 | |
| SCHEMBL152799 | 0.63 | MAPT (0.53) | MAPTALDH1A1NPSR1GAACCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242033-B1 | Compositions comprising arylcyclobutene and polymeric compositions prepared therefrom | DOW CHEMICAL CO (US) | 1994-01-26 | — | — | EP | disclosed |
| US-4965329-A | HEAT RESISTANT POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4826997-A | ADDITION POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| WO-1987005303-A1 | COMPOSITIONS COMPRISING ARYLCYCLOBUTENE AND POLYMERIC COMPOSITIONS PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1987-09-11 | — | — | WO | disclosed |