Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CCR6 | P51684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RGS4 | P49798 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | PTPRF | P10586 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28665945 | 0.77 | MAPT (0.47) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL9322143 | 0.76 | ALDH1A1 (0.41) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL151352 | 0.74 | MAPT (0.50) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL9240802 | 0.71 | MAPT (0.47) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL6741780 | 0.70 | HPGD (0.46) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL1883731 | 0.69 | BACE1 (0.43) | ALDH1A1MAPTGAAHPGDLMNA | |
| SCHEMBL9492806 | 0.69 | GPR84 (0.40) | GAAHPGDKMT2APTPN1CDC25B | |
| SCHEMBL9324699 | 0.68 | MAPT (0.44) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL787853 | 0.68 | MAPT (0.44) | ALDH1A1MAPTNPSR1GAACCR6 | |
| SCHEMBL10396897 | 0.67 | MAPT (0.50) | ALDH1A1MAPTNPSR1GAACCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242033-B1 | Compositions comprising arylcyclobutene and polymeric compositions prepared therefrom | DOW CHEMICAL CO (US) | 1994-01-26 | — | — | EP | disclosed |
| US-4965329-A | HEAT RESISTANT POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4826997-A | ADDITION POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| EP-0242033-A2 | Compositions comprising arylcyclobutene and polymeric compositions prepared therefrom | THE DOW CHEMICAL COMPANY (US) | 1987-10-21 | — | — | EP | disclosed |
| WO-1987005303-A1 | COMPOSITIONS COMPRISING ARYLCYCLOBUTENE AND POLYMERIC COMPOSITIONS PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1987-09-11 | — | — | WO | disclosed |