Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | LTK | P29376 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | MST1R | Q04912 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11643039 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KMT2AKDM4EMEN1USP2 | |
| SCHEMBL9324699 | 0.78 | MAPT (0.44) | PTAFRALDH1A1CA12CA9HPGD | |
| SCHEMBL16369824 | 0.76 | CA12 (0.37) | ALDH1A1KMT2AKDM4EMEN1USP2 | |
| SCHEMBL28738042 | 0.72 | PTAFR (0.41) | PTAFRALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL9342908 | 0.71 | MEN1 (0.45) | ALDH1A1KMT2AMEN1CA12CA9 | |
| SCHEMBL735013 | 0.68 | TLR9 (0.46) | ALDH1A1KMT2AKDM4EMEN1HSD17B10 | |
| SCHEMBL2975487 | 0.66 | RAB9A (0.42) | PTAFRALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL30821340 | 0.65 | BACE1 (0.44) | ALDH1A1KMT2AKDM4EMEN1USP2 | |
| SCHEMBL142991 | 0.63 | PTPN1 (0.55) | ALDH1A1KMT2AKDM4EADORA2AADORA1 | |
| SCHEMBL4783918 | 0.63 | BACE1 (0.55) | ALDH1A1KMT2AMEN1USP2ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0242033-B1 | Compositions comprising arylcyclobutene and polymeric compositions prepared therefrom | DOW CHEMICAL CO (US) | 1994-01-26 | — | — | EP | disclosed |
| US-4965329-A | HEAT RESISTANT POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1990-10-23 | — | — | US | disclosed |
| US-4826997-A | ADDITION POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1989-05-02 | — | — | US | disclosed |
| WO-1987005303-A1 | COMPOSITIONS COMPRISING ARYLCYCLOBUTENE AND POLYMERIC COMPOSITIONS PREPARED THEREFROM | THE DOW CHEMICAL COMPANY (US) | 1987-09-11 | — | — | WO | disclosed |