SCHEMBL28738042

SCHEMBL28738042

O=C1C(c2cccs2)=Cc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTAFR P25105 1/20 0.41
ALDH1A1 P00352 5/20 0.41
KMT2A Q03164 5/20 0.41
KDM4E B2RXH2 3/20 0.41
HSD17B10 Q99714 3/20 0.41
MEN1 O00255 3/20 0.41
USP2 O75604 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
CDC25A P30304 1/20 0.40
CDC25B P30305 1/20 0.40
HPGD P15428 4/20 0.39
HTT P42858 1/20 0.39
LTK P29376 1/20 0.38
CDK5 Q00535 1/20 0.38
MST1R Q04912 1/20 0.38
DYRK1A Q13627 1/20 0.38
CLK4 Q9HAZ1 1/20 0.38
MAOB P27338 1/20 0.37
MAPT P10636 4/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4783918 0.82 BACE1 (0.55) ALDH1A1KMT2AMEN1USP2ADORA2A
SCHEMBL2975487 0.79 RAB9A (0.42) PTAFRALDH1A1KMT2AKDM4EHSD17B10
SCHEMBL3444897 0.78 CDC25B (0.57) ALDH1A1KMT2AKDM4EHSD17B10MEN1
SCHEMBL142991 0.75 PTPN1 (0.55) ALDH1A1KMT2AKDM4EADORA2AADORA1
SCHEMBL7119051 0.74 CDC25B (0.53) ALDH1A1KMT2AKDM4EHSD17B10MEN1
SCHEMBL30821340 0.74 BACE1 (0.44) ALDH1A1KMT2AKDM4EHSD17B10MEN1
SCHEMBL2863479 0.73 PTAFR (0.36) PTAFRALDH1A1KMT2AKDM4EHSD17B10
SCHEMBL9322271 0.72 PTAFR (0.43) PTAFRALDH1A1KMT2AKDM4EHSD17B10
SCHEMBL2975851 0.72 LTA4H (0.39) PTAFRALDH1A1KMT2AKDM4EHSD17B10
SCHEMBL1408501 0.71 BACE1 (0.64) ALDH1A1KMT2AKDM4EHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818729-B Imide conjugated micromolecules based on multi-element aromatic ring, preparation method thereof and application thereof in organic photoelectric devices 华南理工大学 2022-04-22 CN disclosed
CN-110818729-A Imide conjugated micromolecules based on multi-element aromatic ring, preparation method thereof and application thereof in organic photoelectric devices 华南理工大学 2020-02-21 CN disclosed