Diphenylmethane

Diphenylmethane

SCHEMBL9322376

C(CC1CO1)NCCC1CO1.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
MGLL Q99685 2/20 0.45
CALM1 P0DP23 1/20 0.44
CHRM2 P08172 1/20 0.42
CHRM5 P08912 1/20 0.42
CHRM3 P20309 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL9322223 0.89 MEN1 (0.47) MEN1KMT2AMGLLCALM1CHRM2
Diphenylmethane SCHEMBL9321214 0.88 MEN1 (0.46) MEN1KMT2AMGLLCHRM2
SCHEMBL16429266 0.85 MEN1 (0.57) MEN1KMT2ACHRM2
SCHEMBL20695779 0.85 MEN1 (0.57) MEN1KMT2ACHRM2
Diphenylmethane SCHEMBL9322142 0.81 CALM1 (0.48) MGLLCALM1CHRM2CHRM5CHRM3
SCHEMBL9319883 0.77 HTR1A (0.48) KMT2ACHRM2CHRM5CHRM3
SCHEMBL16467051 0.76 MEN1 (0.45) MEN1KMT2A
SCHEMBL9320495 0.76 HTR1A (0.44) MEN1KMT2ACHRM2CHRM5CHRM3
Diphenylmethane SCHEMBL6887153 0.76 CHRM2 (0.47) MEN1KMT2AMGLLCALM1CHRM2
Diphenylmethane SCHEMBL2045851 0.75 CHRM2 (0.56) MEN1KMT2AMGLLCALM1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0336391-B1 Reversibly color-changeable materials TEIJIN LTD (JP) 1994-01-26 EP disclosed
US-5068062-A Crosslinked resin containing 4,4*-diaminodiphenylmethane units with the amine quaternized and an electrolytic material TEIJIN LIMITED (JP) 1991-11-26 US disclosed
EP-0336391-A2 Reversibly color-changeable materials TEIJIN LIMITED (JP) 1989-10-11 EP disclosed