Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523393 | 0.82 | TDP1 (0.48) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL3624272 | 0.82 | TDP1 (0.48) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL523595 | 0.82 | TDP1 (0.48) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL1030793 | 0.77 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL22283421 | 0.77 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL6420860 | 0.77 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL3389806 | 0.77 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL208903 | 0.77 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL16550634 | 0.77 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL1482295 | 0.77 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104893290-B | Radiation-curable silicone composition | 信越化学工业株式会社 | 2020-01-21 | — | — | CN | disclosed |
| EP-0404029-B1 | Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method | GEN ELECTRIC (US) | 1994-02-16 | — | — | EP | disclosed |
| US-4994299-A | Epoxyhaloarylaklsiloxane with polyaryloniumhexafluorometalloid salt photoinitiator | GENERAL ELECTRIC COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0404029-A1 | Substantially odor free, UV curable organopolysiloxane release coating compositions and coating method | GENERAL ELECTRIC COMPANY (US) | 1990-12-27 | — | — | EP | disclosed |