SCHEMBL208903

SCHEMBL208903

Cl[Si](Cl)(Cl)CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
ALOX12 P18054 1/20 0.48
CASP1 P29466 1/20 0.48
HSD17B10 Q99714 1/20 0.48
MAOA P21397 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MAOB P27338 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
KDM1A O60341 1/20 0.46
LMNA P02545 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
HTR1A P08908 1/20 0.46
ADRA2A P08913 1/20 0.46
CYP2C8 P10632 1/20 0.46
CYP2D6 P10635 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6532094 0.97 TDP1 (0.50) TDP1ALDH1A1HPGDALOX15ALOX12
Toluene SCHEMBL18394201 0.89 LMNA (0.46) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL5493502 0.86 FFAR1 (0.48) LMNACYP1A2IDO1TSHRPTGS1
SCHEMBL6848455 0.86 CA2 (0.38) TDP1ALDH1A1MAOAMAOBCYP1A2
SCHEMBL1599233 0.85 SIGMAR1 (0.48) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL1030793 0.84 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL1482295 0.84 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL1203381 0.83 MAOA (0.52) MAOAMAOBCYP2D6HTR2AKCNH2
SCHEMBL5488263 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1
SCHEMBL5482754 0.81 SIGMAR1 (0.52) MAOAMAOBSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1091 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912690-A Silicone resin prepolymer, modified polyester thereof and preparation methods of silicone resin prepolymer and modified polyester 山东省科学院新材料研究所 2025-05-02 CN claimed
US-20250108341-A1 INTERFACIALLY POLYMERISED POLYAMIDE MEMBRANE FOR REVERSE OSMOSIS WITH SILANE ADDITIVE AQUAPORIN A/S (DK) 2025-04-03 US claimed
CN-119331384-A Halogen-free flame-retardant epoxy resin and preparation method thereof 江苏耀鸿电子有限公司 2025-01-21 CN claimed
US-20240401204-A1 METHOD AND COMPOSITION FOR ADJUSTING HYDROPHILICITY OF METAL USING A POLYPHENOL AND A SILANE MODIFIED NANO PARTICULATE OR AMINO ACID AMND SILICA Bulk Chemicals (US) 2024-12-05 US claimed
EP-4466091-A1 INTERFACIALLY POLYMERISED POLYAMIDE MEMBRANE FOR REVERSE OSMOSIS WITH SILANE ADDITIVE Aquaporin A/S (DK) 2024-11-27 EP claimed
CN-116474718-B Hydrophobic lithium-type oxygen-making molecular sieve adsorbent, and preparation method and application thereof 中触媒新材料股份有限公司 2024-10-22 CN claimed
CN-118695898-A Interfacial polymerized polyamide reverse osmosis membrane with silane additive 水通道蛋白有限公司 2024-09-24 CN claimed
CN-117343638-A Porous spin-on dielectric coating materials from silicon-containing polymers 上海艾深斯科技有限公司 2024-01-05 CN claimed
CN-116589800-A Flame-retardant PS diffusion plate and production process thereof 佛山市德联邦盛光电科技股份有限公司 2023-08-15 CN claimed
CN-116500863-A Composition of combined ARC and Si-based hard mask film 上海艾深斯科技有限公司 2023-07-28 CN claimed
CN-1877879-A Barrier layer for an organic electronic device XEROX CORP (US) 2006-12-13 CN claimed
US-20060273302-A1 Barrier layer for an organic electronic device XEROX CORPORATION 2006-12-07 US claimed
US-20050258571-A1 Method of imprinting shadow mask nanostructures for display pixel segregation AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2005-11-24 US claimed
EP-1520574-A2 Flexible medical container packaging BRACCO INTERNATIONAL B.V. (NL) 2005-04-06 EP claimed
US-6242628-B1 THAT ARE LOW OR FREE OF ACIDIC CHLORIDE BY REACTING CHLOROSILANE WITH AN ALCOHOL IN WATER-FREE AND SOLVENT-FREE PHASE AND REMOVING THE LIBERATED HYDROGEN CHLORIDE; USED AS ADHESION PROMOTORS DEGUSSA-HUELS AKTIENGESELLSCHAFT (DE) 2001-06-05 US claimed
US-5113001-A Process for preparing sulfophenylalkylsiloxanes or sulfonaphthylalkylsiloxanes BASF CORPORATION (US) 1992-05-12 US claimed
US-5091548-A Solventless process for preparing sulfophenethylsiloxane or sulfonaphyhylethylsiloxanes BASF CORPORATION (US) 1992-02-25 US claimed
US-4575559-A Process for preparing certain sulfophenethylsiloxanes BASF WYANDOTTE CORPORATION (US) 1986-03-11 US claimed
US-4476291-A Resins containing β-phenylethyl trifunctional siloxy units and method for making GENERAL ELECTRIC COMPANY (US) 1984-10-09 US claimed
US-4228092-A BY ALCOHOL ESTERIFICATION DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1980-10-14 US claimed