SCHEMBL9323005

SCHEMBL9323005

Cc1cc(O)nc(-n2[nH]c(C)cc2=O)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.54
ALPL P05186 2/20 0.54
ALDH1A1 P00352 11/20 0.50
KDM4E B2RXH2 10/20 0.50
MAPT P10636 7/20 0.50
GAA P10253 3/20 0.50
HTT P42858 2/20 0.50
MEN1 O00255 2/20 0.50
LMNA P02545 4/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
ALKBH3 Q96Q83 1/20 0.42
KDM5A P29375 1/20 0.41
KDM2B Q8NHM5 1/20 0.41
KDM4C Q9H3R0 1/20 0.41
RECQL P46063 2/20 0.41
POLB P06746 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RAD51 Q06609 1/20 0.36
ENPP3 O14638 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14966715 0.63 ALDH1A1 (0.59) KMT2AALPLALDH1A1KDM4EMAPT
Methyl Alcohol SCHEMBL1028813 0.63 MAPT (0.69) KMT2AALDH1A1KDM4EMAPTGAA
SCHEMBL11883268 0.62 MAPT (0.55) KMT2AALDH1A1KDM4EMAPTGAA
SCHEMBL9323015 0.62 KDM4E (0.36) KMT2AALDH1A1KDM4EMAPTGAA
SCHEMBL20042186 0.62 CASP1 (0.51) KMT2AALDH1A1KDM4EMAPTMEN1
SCHEMBL34121 0.62 ALDH1A1 (0.68) KMT2AALPLALDH1A1KDM4EMAPT
SCHEMBL9150171 0.62 ALDH1A1 (0.68) KMT2AALPLALDH1A1KDM4EMAPT
SCHEMBL5425653 0.62 ALDH1A1 (0.68) KMT2AALPLALDH1A1KDM4EMAPT
SCHEMBL486125 0.62 MAPT (0.73) KMT2AALPLALDH1A1KDM4EMAPT
SCHEMBL692943 0.62 ALDH1A1 (0.59) KMT2AALDH1A1KDM4EMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0583004-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-02-16 EP disclosed
US-3865825-A Pyrimidinylphrazolone derivative and process of preparing the same DAIICHI SEIYAKU CO 1975-02-11 US disclosed