SCHEMBL9323015

SCHEMBL9323015

CC1=NN(c2nc(C)cc(O)n2)CC1=O

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.36
HSD17B10 Q99714 3/20 0.36
NPSR1 Q6W5P4 2/20 0.36
HPGD P15428 2/20 0.36
USP2 O75604 1/20 0.36
ALDH1A1 P00352 5/20 0.35
MAPT P10636 1/20 0.35
HCRTR1 O43613 2/20 0.33
HCRTR2 O43614 2/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
GAA P10253 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GBA1 P04062 1/20 0.32
RAB9A P51151 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11883268 0.68 MAPT (0.55) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL9510339 0.65 NR4A1 (0.45) KDM4EHSD17B10NPSR1USP2ALDH1A1
SCHEMBL20042186 0.65 CASP1 (0.51) KDM4EHSD17B10NPSR1HPGDUSP2
SCHEMBL11851842 0.65 KMT2A (0.70) HSD17B10NPSR1ALDH1A1MAPTKMT2A
SCHEMBL7786530 0.63 F2 (0.42) NPSR1HPGDALDH1A1MAPTKMT2A
SCHEMBL9323005 0.62 KMT2A (0.54) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL5425655 0.62 MAPT (0.43) KDM4EALDH1A1MAPTKMT2AMEN1
SCHEMBL11579395 0.61 KMT2A (0.51) KDM4ENPSR1ALDH1A1MAPTKMT2A
SCHEMBL11290209 0.61 KMT2A (0.43) KDM4EHPGDALDH1A1MAPTKMT2A
SCHEMBL9309242 0.60 KAT8 (0.41) KDM4EHSD17B10NPSR1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0583004-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-02-16 EP disclosed