Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RHEB | Q15382 | 2/20 | 0.39 |
| ▸ | CCR2 | P41597 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370836 | 0.79 | ALDH1A1 (0.43) | LMNARHEBPTGS1PTGS2ALDH1A1 | |
| SCHEMBL14920304 | 0.76 | PTGS1 (0.44) | RHEBPTGS1PTGS2ALDH1A1KDM4E | |
| SCHEMBL9114683 | 0.75 | PTGS1 (0.33) | RHEBPTGS1PTGS2 | |
| SCHEMBL8492178 | 0.74 | LMNA (0.41) | LMNAALDH1A1KDM4EHSD17B10ALOX15 | |
| SCHEMBL8406918 | 0.73 | ALDH1A1 (0.57) | LMNACCR2PTGS2ALDH1A1CYP2C9 | |
| SCHEMBL8387170 | 0.72 | LMNA (0.51) | LMNAALDH1A1ALOX15 | |
| SCHEMBL8388401 | 0.72 | LMNA (0.54) | LMNAALDH1A1KDM4EHSD17B10CA12 | |
| SCHEMBL8491404 | 0.72 | TSHR (0.55) | LMNACCR2PTGS2ALDH1A1CYP2C9 | |
| SCHEMBL9322192 | 0.71 | ALDH1A1 (0.45) | LMNAPTGS1PTGS2ALDH1A1CYP2C9 | |
| SCHEMBL8070593 | 0.70 | LMNA (0.47) | LMNACCR2MCL1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371064-A | Herbicidal 4-benzoylisoxazole derivatives | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0580439-A1 | Benzoylisoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-01-26 | — | — | EP | disclosed |