Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 2/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492137 | 0.82 | CES2 (0.44) | LMNAALDH1A1ALOX15ACLY | |
| SCHEMBL8387249 | 0.79 | ALOX15 (0.39) | LMNAALDH1A1ALOX15MYC | |
| SCHEMBL8388401 | 0.79 | LMNA (0.54) | LMNAALDH1A1TSHRTP53CASP1 | |
| SCHEMBL7235842 | 0.77 | LMNA (0.47) | LMNANOTUMACLY | |
| SCHEMBL1495458 | 0.77 | LMNA (0.53) | LMNANOTUMALDH1A1TSHRTP53 | |
| SCHEMBL8387593 | 0.77 | LMNA (0.49) | LMNAALDH1A1TSHRTP53CASP1 | |
| SCHEMBL977553 | 0.77 | ALOX15 (0.40) | LMNANOTUMALDH1A1ALOX15CLCN2 | |
| SCHEMBL7551812 | 0.76 | LMNA (0.44) | LMNANOTUMCLCN2HPGDSORT1 | |
| SCHEMBL20721983 | 0.75 | HPGD (0.55) | LMNANOTUMALDH1A1TSHRTP53 | |
| SCHEMBL8491404 | 0.75 | TSHR (0.55) | LMNANOTUMALDH1A1TSHRALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5856274-A | 4-benzoyl isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |
| EP-0682659-B1 | 4-Benzoyl isoxazole derivatives, their preparation and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0682659-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES. | RHONE POULENC AGRICULTURE (GB) | 1995-11-22 | — | — | EP | disclosed |
| US-5371064-A | Herbicidal 4-benzoylisoxazole derivatives | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-12-06 | — | — | US | disclosed |
| WO-1994018179-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD (GB) | 1994-08-18 | — | — | WO | disclosed |
| EP-0580439-A1 | Benzoylisoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-01-26 | — | — | EP | disclosed |