Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | IDH2 | P48735 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367106 | 0.86 | KMT2A (0.47) | KMT2AIDH2ARMRGPRX1ALDH1A1 | |
| SCHEMBL9363632 | 0.83 | KMT2A (0.49) | KMT2AIDH2ARCA1CA2 | |
| SCHEMBL9363404 | 0.81 | KMT2A (0.42) | KMT2AIDH2ARMRGPRX1ALDH1A1 | |
| SCHEMBL9323154 | 0.80 | KMT2A (0.49) | KMT2AIDH2ARMRGPRX1ALDH1A1 | |
| SCHEMBL9363767 | 0.79 | KMT2A (0.47) | KMT2AIDH2ARCA1CA2 | |
| SCHEMBL9499710 | 0.79 | KMT2A (0.45) | KMT2AIDH2MRGPRX1ALDH1A1HTT | |
| SCHEMBL9364278 | 0.78 | IDH2 (0.39) | KMT2AIDH2ARCA12CA1 | |
| SCHEMBL9363735 | 0.77 | KMT2A (0.46) | KMT2AIDH2CA1CA2CA4 | |
| SCHEMBL9363682 | 0.77 | KMT2A (0.51) | KMT2AIDH2ARCA12CA1 | |
| SCHEMBL9499786 | 0.77 | KMT2A (0.46) | KMT2AIDH2ARMRGPRX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447013-B1 | Fluorobenzene sulphonamides | SCHERING AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |
| EP-0447013-A1 | Fluorobenzene sulphonamides | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-18 | — | — | EP | disclosed |