Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | IDH2 | P48735 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 2/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9364278 | 0.90 | IDH2 (0.39) | KMT2AIDH2ARGCGRMCL1 | |
| SCHEMBL9363632 | 0.88 | KMT2A (0.49) | KMT2AIDH2ARMCL1MRGPRX1 | |
| SCHEMBL9367195 | 0.86 | KMT2A (0.47) | KMT2AIDH2ARMRGPRX1MEN1 | |
| SCHEMBL9323154 | 0.85 | KMT2A (0.49) | KMT2AIDH2ARMRGPRX1MEN1 | |
| SCHEMBL9363404 | 0.85 | KMT2A (0.42) | KMT2AIDH2ARMRGPRX1NPSR1 | |
| SCHEMBL9363911 | 0.83 | IDH2 (0.41) | KMT2AIDH2MRGPRX1LMNAFFAR4 | |
| SCHEMBL9363735 | 0.82 | KMT2A (0.46) | KMT2AIDH2MRGPRX1 | |
| SCHEMBL9363767 | 0.81 | KMT2A (0.47) | KMT2AIDH2ARMRGPRX1 | |
| SCHEMBL9368626 | 0.79 | IDH2 (0.40) | KMT2AIDH2ARMCL1MRGPRX1 | |
| SCHEMBL9367199 | 0.79 | SLC22A12 (0.45) | IDH2ARGCGRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447013-B1 | Fluorobenzene sulphonamides | SCHERING AG (DE) | 1994-08-03 | — | — | EP | disclosed |
| US-5210290-A | NMR diagnostic aid | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-11 | — | — | US | disclosed |