Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | LTK | P29376 | 1/20 | 0.34 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871239 | 0.68 | NOS3 (0.33) | — | |
| SCHEMBL6542445 | 0.68 | CLK4 (0.34) | CLK4NTRK1LTKTYRO3NTRK2 | |
| SCHEMBL5039678 | 0.67 | CLK4 (0.41) | CLK4NTRK1LTKTYRO3NTRK2 | |
| SCHEMBL9325193 | 0.62 | NTRK1 (0.32) | CLK4NTRK1LTKTYRO3NTRK2 | |
| SCHEMBL5044668 | 0.61 | ATAD2 (0.46) | KDM4EMAPT | |
| SCHEMBL12032548 | 0.60 | — | — | |
| SCHEMBL5173348 | 0.60 | — | — | |
| SCHEMBL6403829 | 0.59 | BACE1 (0.49) | KDM4EBACE1 | |
| SCHEMBL31210378 | 0.58 | ADORA2A (0.46) | CLK4NTRK1LTKTYRO3NTRK2 | |
| SCHEMBL9282809 | 0.58 | CLK4 (0.38) | CLK4NTRK1LTKTYRO3NTRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292733-A | Cephalosporin compounds | LUCKY LIMITED (KR) | 1994-03-08 | — | — | US | disclosed |
| EP-0508375-A2 | Novel cephalosporin compounds and processes for preparation thereof | LUCKY LTD. (KR) | 1992-10-14 | — | — | EP | disclosed |