Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3732806 | 0.81 | MAPT (0.48) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR | |
| SCHEMBL9323810 | 0.79 | HTT (0.38) | MAPTSIGMAR1HTTCA12CA2 | |
| Hydrochloric Acid SCHEMBL17710416 | 0.79 | MAPT (0.46) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR | |
| SCHEMBL2015299 | 0.77 | MAPT (0.44) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR | |
| SCHEMBL11041549 | 0.77 | MAPT (0.44) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR | |
| SCHEMBL30288278 | 0.77 | ALDH1A1 (0.44) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR | |
| SCHEMBL6702352 | 0.77 | TAAR1 (0.46) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR | |
| SCHEMBL15114128 | 0.77 | MAPT (0.50) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR | |
| SCHEMBL9572856 | 0.74 | SIGMAR1 (0.41) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR | |
| SCHEMBL11442104 | 0.74 | SIGMAR1 (0.45) | ALDH1A1MAPTSIGMAR1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0432988-B1 | Hydrocarbylphenyl diaminodithiol derivatives | AMERSHAM INT PLC (GB) | 1994-02-16 | — | — | EP | disclosed |
| US-5080884-A | Hydrocarbylphenyl diaminodithiol radionuclide complexes and their use in imaging | MEDI-PHYSICS, INC. (US) | 1992-01-14 | — | — | US | disclosed |
| US-5026913-A | For imaging organs | MEDI-PHYSICS, INC. (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0432988-A1 | Hydrocarbylphenyl diaminodithiol derivatives | AMERSHAM INTERNATIONAL plc (GB) | 1991-06-19 | — | — | EP | disclosed |