Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11442104 | 0.83 | SIGMAR1 (0.45) | MAPTALDH1A1SIGMAR1L3MBTL1TSHR | |
| SCHEMBL9572856 | 0.83 | SIGMAR1 (0.41) | MAPTALDH1A1SIGMAR1L3MBTL1TSHR | |
| SCHEMBL3732806 | 0.81 | MAPT (0.48) | MAPTALDH1A1SIGMAR1L3MBTL1TSHR | |
| SCHEMBL20626603 | 0.81 | MAPT (0.50) | MAPTALDH1A1SIGMAR1L3MBTL1TSHR | |
| Hydrochloric Acid SCHEMBL17710416 | 0.79 | MAPT (0.46) | MAPTALDH1A1SIGMAR1L3MBTL1TSHR | |
| SCHEMBL11478052 | 0.78 | CTSD (0.41) | L3MBTL1KMT2ACTSD | |
| SCHEMBL13185539 | 0.78 | HPGD (0.48) | MAPTALDH1A1SIGMAR1L3MBTL1MEN1 | |
| SCHEMBL21799681 | 0.78 | MAPT (0.39) | MAPTALDH1A1L3MBTL1TSHRMEN1 | |
| SCHEMBL13167597 | 0.78 | CA1 (0.42) | MAPTTSHRLMNAMEN1KMT2A | |
| SCHEMBL21379732 | 0.78 | MAPT (0.41) | MAPTALDH1A1SIGMAR1L3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946180-A | Chiral iridium complex and preparation method and application thereof | 南方科技大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-113041913-A | Simple mixing processing device for high polymer material and auxiliary agent screening method thereof | 北京理工大学 | 2021-06-29 | — | — | CN | disclosed |
| US-20190330189-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2019-10-31 | — | — | US | disclosed |
| CN-104379559-B | Compound (I) | 葛兰素集团有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-104379559-A | Novel compounds | GLAXO GROUP LTD | 2015-02-25 | — | — | CN | disclosed |
| US-4468526-A | Process for the preparation of thiuram disulfides | AKZONA INCORPORATED (US) | 1984-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330189-A1 | ANTIBACTERIAL COMPOUNDS | FDPS, SQOR, NDUFS3 | MAPT 1437/4885ALDH1A1 1869/4885SIGMAR1 2451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.