Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 10/20 | 0.74 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.74 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.74 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.74 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.62 |
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.61 |
| ▸ | OSBP | P22059 | 1/20 | 0.60 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.60 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226390 | 1.00 | GPBAR1 (0.74) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL16226649 | 1.00 | GPBAR1 (0.74) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL16227156 | 0.94 | GPBAR1 (0.77) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL16226417 | 0.94 | GPBAR1 (0.77) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL19519612 | 0.92 | GPBAR1 (0.74) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL16226880 | 0.92 | GPBAR1 (0.74) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL17806641 | 0.92 | GPBAR1 (0.74) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL6560685 | 0.92 | GPBAR1 (0.74) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL15185968 | 0.92 | GPBAR1 (0.74) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A | |
| SCHEMBL12290838 | 0.92 | GPBAR1 (0.74) | GPBAR1NR1H4SLC10A2TBXA2RPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10723672-B2 | Normal alpha olefin synthesis using dehydroformylation or dehydroxymethylation | CHERVON PHILLIPS CHEMICAL COMPANY LP (US) | 2020-07-28 | — | — | US | disclosed |
| US-20190263729-A1 | Normal Alpha Olefin Synthesis Using Dehydroformylation or Dehydroxymethylation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2019-08-29 | — | — | US | disclosed |
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
| US-5304551-A | Administering topically to treat ringworm or athlets foot | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1994-04-19 | — | — | US | disclosed |
| EP-0527832-A1 | ANTI-FUNGAL BILE ACID DERIVATIVES | LOUGHBOROUGH UNIVERSITY OF TECHNOLOGY (GB) | 1993-02-24 | — | — | EP | disclosed |
| WO-1991016898-A1 | ANTI-FUNGAL BILE ACID DERIVATIVES | BRITISH TECHNOLOGY GROUP LTD (GB) | 1991-11-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | GPBAR1 77/4885NR1H4 131/4885SLC10A2 3818/4885 |
| US-10723672-B2 | Normal alpha olefin synthesis using dehydroformylation or dehydroxymethylation | ADH1A, ADH1C, DHPS | GPBAR1 1306/4885NR1H4 1287/4885SLC10A2 2741/4885 |
| US-20190263729-A1 | Normal Alpha Olefin Synthesis Using Dehydroformylation or Dehydroxymethylation | ADH1A, ADH1C, DHPS | GPBAR1 1306/4885NR1H4 1287/4885SLC10A2 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.