Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7034611 | 0.85 | CA1 (0.45) | KMT2ACA1CA2CA5ACA9 | |
| SCHEMBL7029203 | 0.85 | CA1 (0.57) | KMT2ACA1CA2CA5ACA9 | |
| SCHEMBL12724024 | 0.81 | KMT2A (0.47) | KMT2ACA1CA2CA5ACA9 | |
| SCHEMBL2576801 | 0.81 | ALB (0.53) | CA1CA2CA9TSHRLMNA | |
| SCHEMBL31046855 | 0.81 | ALB (0.53) | CA1CA2CA9TSHRLMNA | |
| SCHEMBL27745299 | 0.80 | ALDH1A1 (0.61) | KMT2ACA1CA2CA5ACA9 | |
| SCHEMBL27350430 | 0.79 | ALOX15 (0.55) | TSHRALDH1A1HPGDPOLB | |
| SCHEMBL7029275 | 0.79 | KMT2A (0.42) | KMT2ACA1CA2CA5ACA9 | |
| SCHEMBL221875 | 0.78 | TSHR (0.50) | KMT2ACA1CA2CA5ACA9 | |
| SCHEMBL1340852 | 0.77 | CES2 (0.61) | KMT2ACA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371064-A | Herbicidal 4-benzoylisoxazole derivatives | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0580439-A1 | Benzoylisoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LTD. (GB) | 1994-01-26 | — | — | EP | disclosed |