Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | FPR3 | P25089 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322304 | 0.93 | CARM1 (0.41) | KDM4EUSP2CARM1PRMT6PRMT8 | |
| SCHEMBL21730428 | 0.91 | HRH3 (0.44) | KDM4EUSP2CARM1PRMT6PRMT8 | |
| SCHEMBL21730510 | 0.91 | HRH3 (0.44) | KDM4EUSP2CARM1PRMT6PRMT8 | |
| SCHEMBL9321377 | 0.91 | HRH3 (0.42) | CARM1PRMT6PRMT8FPR3FPR2 | |
| SCHEMBL9322327 | 0.91 | HRH3 (0.42) | CARM1PRMT6PRMT8FPR3FPR2 | |
| SCHEMBL9321403 | 0.91 | HRH3 (0.42) | CARM1PRMT6PRMT8FPR3FPR2 | |
| SCHEMBL20979276 | 0.90 | CARM1 (0.39) | KDM4EUSP2CARM1PRMT6PRMT8 | |
| SCHEMBL26941612 | 0.90 | CARM1 (0.41) | KDM4EUSP2CARM1PRMT6PRMT8 | |
| SCHEMBL9322707 | 0.89 | FPR3 (0.40) | CARM1PRMT6PRMT8FPR3FPR2 | |
| SCHEMBL21730424 | 0.88 | HRH3 (0.41) | KDM4EUSP2CARM1PRMT6PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | claimed |
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| EP-0235942-B1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO (JP) | 1994-03-23 | — | — | EP | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |
| EP-0235942-A1 | Alkylenediamine derivatives | NIPPON CHEMIPHAR CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |