Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | FLT1 | P17948 | 1/20 | 0.33 |
| ▸ | FLT4 | P35916 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324399 | 0.91 | CDK1 (0.39) | STAT3DHODHCDK1CDK4CCND1 | |
| SCHEMBL9422376 | 0.87 | DHODH (0.34) | DHODHPDE2AEPHX2 | |
| SCHEMBL9323629 | 0.85 | DHODH (0.35) | DHODHCDK1CDK4CCND1CDK2 | |
| SCHEMBL4894785 | 0.83 | F10 (0.39) | STAT3DHODHSLC6A9NPC1RAB9A | |
| SCHEMBL123795 | 0.83 | F10 (0.39) | STAT3DHODHSLC6A9NPC1RAB9A | |
| SCHEMBL9324479 | 0.82 | DHODH (0.38) | DHODHRAB9AEPHX2MAPT | |
| SCHEMBL27392585 | 0.82 | GPBAR1 (0.38) | STAT3NPC1RAB9AFLT1FLT4 | |
| SCHEMBL9115727 | 0.81 | PTGDR2 (0.37) | STAT3DHODHEPHX2HPGD | |
| SCHEMBL8489076 | 0.81 | DHODH (0.35) | STAT3DHODHCDK1CDK4CCND1 | |
| SCHEMBL7573670 | 0.80 | SLC6A9 (0.35) | DHODHCDK1CDK4CCND1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371063-A | Herbicidal 4-benzoylisoxazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-06 | — | — | US | claimed |
| CN-1093359-A | New herbicides | RHONE POULENC AGRICULTURE (GB) | 1994-10-12 | — | — | CN | claimed |
| EP-0609797-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| US-5371063-A | Herbicidal 4-benzoylisoxazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0609797-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |