Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 3/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | MRGPRX1 | Q96LB2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323637 | 0.91 | STAT3 (0.35) | CDK1CDK4CCND1CDK2STAT3 | |
| SCHEMBL9323629 | 0.85 | DHODH (0.35) | CDK1CDK4CCND1CDK2DHODH | |
| SCHEMBL8489076 | 0.83 | DHODH (0.35) | CDK1CDK4CCND1CDK2STAT3 | |
| SCHEMBL4894785 | 0.81 | F10 (0.39) | STAT3DHODHNPC1RAB9AKMT2A | |
| SCHEMBL123795 | 0.81 | F10 (0.39) | STAT3DHODHNPC1RAB9AKMT2A | |
| SCHEMBL9324479 | 0.80 | DHODH (0.38) | DHODHRAB9AALDH1A1 | |
| SCHEMBL9422376 | 0.80 | DHODH (0.34) | DHODHPOLBPTGDR2 | |
| SCHEMBL7691232 | 0.79 | C5AR1 (0.40) | CDK1CDK4CCND1CDK2TSHR | |
| SCHEMBL7573670 | 0.78 | SLC6A9 (0.35) | CDK1CDK4CCND1CDK2DHODH | |
| SCHEMBL8814817 | 0.77 | GAA (0.39) | DHODHMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371063-A | Herbicidal 4-benzoylisoxazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-06 | — | — | US | claimed |
| EP-0609797-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | claimed |
| US-5371063-A | Herbicidal 4-benzoylisoxazoles | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1994-12-06 | — | — | US | disclosed |
| EP-0609797-A1 | 4-Benzoyl isoxazoles and their use as herbicides | RHONE POULENC AGRICULTURE LTD. (GB) | 1994-08-10 | — | — | EP | disclosed |