Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | PEPD | P12955 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13995210 | 0.84 | LTA4H (0.48) | LTA4HPEPDMMP3POLBALDH1A1 | |
| SCHEMBL13995592 | 0.84 | LTA4H (0.48) | LTA4HPEPDMMP3POLBALDH1A1 | |
| SCHEMBL19571179 | 0.84 | LTA4H (0.48) | LTA4HPEPDMMP3POLBALDH1A1 | |
| SCHEMBL9288792 | 0.80 | LTA4H (0.46) | LTA4HPEPDNR1I2POLBALDH1A1 | |
| SCHEMBL4230937 | 0.78 | LTA4H (0.48) | LTA4HPEPDNR1I2POLBALDH1A1 | |
| SCHEMBL7833954 | 0.78 | LTA4H (0.48) | LTA4HPEPDNR1I2POLBALDH1A1 | |
| SCHEMBL4220647 | 0.78 | LTA4H (0.48) | LTA4HPEPDNR1I2POLBALDH1A1 | |
| SCHEMBL9323743 | 0.77 | THRA (0.40) | LTA4HPOLBALDH1A1GAARAB9A | |
| SCHEMBL14115082 | 0.77 | NR1I2 (0.54) | LTA4HNR1I2POLBFKBP1A | |
| SCHEMBL15434618 | 0.77 | NR1I2 (0.54) | LTA4HNR1I2POLBFKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |