Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321324 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1GAA | |
| SCHEMBL24633509 | 0.83 | TP53 (0.47) | THRATHRBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9323599 | 0.80 | BCHE (0.49) | SMN1; SMN2ALDH1A1LTA4HHSD17B10 | |
| SCHEMBL9322337 | 0.79 | KCNA3 (0.43) | — | |
| SCHEMBL9322401 | 0.78 | GAA (0.40) | THRATHRBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9322294 | 0.78 | BCHE (0.50) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9323648 | 0.77 | LTA4H (0.42) | ALDH1A1GAALTA4HPOLBRAB9A | |
| SCHEMBL9322225 | 0.76 | THRA (0.40) | THRATHRBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL13472645 | 0.75 | THRA (0.56) | THRATHRBTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9323544 | 0.75 | KCNA3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310902-A | Glutamate blockers | NIPPON CHEMIPHAR CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |
| US-5070196-A | GLUTAMATE BLOCKERS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1991-12-03 | — | — | US | disclosed |