SCHEMBL9323975

SCHEMBL9323975

COCc1nc(Cl)c(CCCCl)[nH]1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.31
CACNA1H O95180 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9324887 0.72 SMN1; SMN2 (0.37) SMN1; SMN2CACNA1H
SCHEMBL21095413 0.66 ALDH1A1 (0.39) SMN1; SMN2CACNA1H
SCHEMBL7451055 0.65 SMN1; SMN2 (0.37) SMN1; SMN2CACNA1H
SCHEMBL309 0.64 CACNA1H (0.35) CACNA1H
SCHEMBL8790906 0.63 ALDH1A1 (0.42)
SCHEMBL225 0.59 ALDH1A1 (0.41)
SCHEMBL20470648 0.58 SMN1; SMN2 (0.41) SMN1; SMN2CACNA1H
SCHEMBL18663592 0.58 GAA (0.67) CACNA1H
SCHEMBL606 0.57 PDK2 (0.37)
SCHEMBL585424 0.57 SMN1; SMN2 (0.44) SMN1; SMN2CACNA1H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365030-B1 Imidazole compound and process for preparing the same ISHIHARA SANGYO KAISHA (JP) 1994-01-26 EP disclosed
US-5023336-A Fungicides, biocides ISHIHARA SANGYO KAISHA LTD. (JP) 1991-06-11 US disclosed
EP-0365030-A1 Imidazole compound and process for preparing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1990-04-25 EP disclosed