SCHEMBL9324064

SCHEMBL9324064

CCN(Oc1ccccc1Oc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
TSPO P30536 1/20 0.46
LPAR1 Q92633 5/20 0.46
LPAR5 Q9H1C0 5/20 0.46
CTNNB1 P35222 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
POLB P06746 2/20 0.43
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
TTR P02766 1/20 0.42
SLC6A3 Q01959 1/20 0.41
KCNH2 Q12809 1/20 0.41
ALDH1A1 P00352 2/20 0.41
ADRA2C P18825 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27996680 0.86 SLC6A2 (0.47) LMNAMAPTTSPOLPAR1LPAR5
SCHEMBL11310669 0.83 ALDH1A1 (0.50) LMNAALDH1A1
SCHEMBL9633108 0.83 CXCL8 (0.50) LPAR1LPAR5L3MBTL1
SCHEMBL2065189 0.83 LMNA (0.43) LMNAMAPTL3MBTL1ALDH1A1TSHR
SCHEMBL11333945 0.80 HTT (0.44) LMNAMAPTTSPOCTNNB1L3MBTL1
SCHEMBL13736417 0.74 LPAR1 (0.40) LPAR1LPAR5L3MBTL1SLC6A2SLC6A4
Butane SCHEMBL6289475 0.71 CTNNB1 (0.51) LMNAMAPTTSPOCTNNB1L3MBTL1
SCHEMBL1345670 0.71 ELANE (0.51) LMNAMAPTTSPOCTNNB1L3MBTL1
SCHEMBL14134443 0.71 MAPT (0.81) LMNAMAPTLPAR1LPAR5CTNNB1
SCHEMBL11312887 0.71 ELANE (0.55) LMNAMAPTL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0394191-B1 Sulfenylated carbamic acid esters CIBA GEIGY AG (CH) 1994-02-02 EP claimed