Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102610 | 0.78 | KEAP1 (0.47) | KEAP1NFE2L2PARP14L3MBTL1GLO1 | |
| SCHEMBL7555603 | 0.71 | BRD4 (0.42) | KEAP1NFE2L2GLO1ALOX15HTT | |
| SCHEMBL1512573 | 0.71 | ACHE (0.47) | BCHECES1CDK1 | |
| SCHEMBL8604698 | 0.69 | MAPT (0.66) | KEAP1NFE2L2PARP14L3MBTL1NR3C1 | |
| SCHEMBL28164407 | 0.69 | KEAP1 (0.45) | KEAP1NFE2L2PARP14L3MBTL1NR3C1 | |
| SCHEMBL29904739 | 0.69 | KEAP1 (0.65) | KEAP1NFE2L2L3MBTL1NR3C1PGR | |
| SCHEMBL2068498 | 0.69 | KEAP1 (0.65) | KEAP1NFE2L2L3MBTL1NR3C1PGR | |
| SCHEMBL5673475 | 0.68 | KDM1A (0.51) | KEAP1NFE2L2PARP14L3MBTL1NR3C1 | |
| SCHEMBL16569613 | 0.68 | CYP19A1 (0.56) | L3MBTL1HTTKDM4EBCHECES1 | |
| SCHEMBL9091651 | 0.68 | KEAP1 (0.47) | KEAP1NFE2L2PARP14L3MBTL1NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0583004-A1 | Silver halide photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1994-02-16 | — | — | EP | disclosed |