Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947083 | 0.86 | BACE1 (0.36) | BACE1 | |
| SCHEMBL944396 | 0.79 | NCOA1 (0.33) | — | |
| SCHEMBL6920536 | 0.79 | BACE1 (0.39) | BACE1 | |
| SCHEMBL944383 | 0.77 | — | — | |
| SCHEMBL932175 | 0.73 | BACE1 (0.51) | BACE1APP | |
| SCHEMBL945865 | 0.72 | ALDH1A1 (0.35) | BACE1 | |
| SCHEMBL946379 | 0.69 | — | — | |
| SCHEMBL943316 | 0.69 | ALDH1A1 (0.34) | BACE1 | |
| SCHEMBL3359122 | 0.68 | BACE1 (0.36) | BACE1APP | |
| SCHEMBL3359125 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011002407-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |
| WO-2011002407-A1 | NOVEL COMPOUNDS FOR TREATMENT OF NEURODEGENERATION ASSOCIATED WITH DISEASES, SUCH AS ALZHEIMER'S DISEASE OR DEMENTIA | ASTRAZENECA AB (SE) | 2011-01-06 | — | — | WO | disclosed |