Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323395 | 0.86 | LMNA (0.59) | ALDH1A1LMNAMAPTMAPK1CES2 | |
| SCHEMBL9323727 | 0.85 | LMNA (0.68) | ALDH1A1LMNAMAPTMAPK1PRKCA | |
| SCHEMBL18651161 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1CES2 | |
| SCHEMBL4622341 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1CES2 | |
| SCHEMBL3857221 | 0.84 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPTMAPK1CES2 | |
| SCHEMBL24220782 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1TSHR | |
| SCHEMBL11724941 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1CES2 | |
| SCHEMBL10087903 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1ALOX15 | |
| SCHEMBL6900350 | 0.80 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTMAPK1ALOX15 | |
| SCHEMBL120124 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409234-B1 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | CHISSO CORP (JP) | 1994-02-16 | — | — | EP | disclosed |
| US-5164112-A | Optical activity, ferroelectric, short response times | CHISSO CORPORATION (JP) | 1992-11-17 | — | — | US | disclosed |
| EP-0409234-A2 | Alpha-hydroxyketone derivatives, liquid crystal compositions containing said derivatives, and liquid crystal devices using said compositions | Chisso Corporation (JP) | 1991-01-23 | — | — | EP | disclosed |