SCHEMBL4622341

SCHEMBL4622341

CCCC(=O)OC(C)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.48
LMNA P02545 5/20 0.45
HDAC1 Q13547 2/20 0.40
HDAC2 Q92769 2/20 0.40
FFAR3 O14843 1/20 0.40
HDAC3 O15379 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
MAPK1 P28482 3/20 0.38
MAPT P10636 2/20 0.38
MMP1 P03956 1/20 0.36
MMP2 P08253 1/20 0.36
MMP3 P08254 1/20 0.36
MMP9 P14780 1/20 0.36
MMP13 P45452 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
CHRM1 P11229 1/20 0.36
AKR1A1 P14550 1/20 0.36
CHRM3 P20309 1/20 0.36
HTR2A P28223 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18651161 1.00 ALDH1A1 (0.48) ALDH1A1LMNAHDAC1HDAC2FFAR3
SCHEMBL20061760 0.92 ALDH1A1 (0.41) ALDH1A1LMNAHDAC1HDAC2FFAR3
SCHEMBL20061759 0.92 ALDH1A1 (0.41) ALDH1A1LMNAHDAC1HDAC2FFAR3
SCHEMBL2608669 0.88 LMNA (0.40) ALDH1A1LMNAMAPTMMP1MMP2
SCHEMBL7110445 0.88 LMNA (0.40) ALDH1A1LMNAMAPTMMP1MMP2
SCHEMBL7336193 0.87 LMNA (0.57) ALDH1A1LMNAMAPK1MAPTCYP1A2
Pyridine SCHEMBL8167435 0.86 ALDH1A1 (0.36) ALDH1A1LMNAMAPK1MAPTTDP1
SCHEMBL17027867 0.85 LMNA (0.66) ALDH1A1LMNAMAPK1MAPTCYP1A2
SCHEMBL9324751 0.84 ALDH1A1 (0.50) ALDH1A1LMNAHDAC1HDAC2FFAR3
Acetic Acid SCHEMBL22769870 0.84 LMNA (0.38) ALDH1A1LMNAFFAR3MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115745946-B Low-temperature preparation method of glycolide and lactide 中国科学院长春应用化学研究所 2024-03-26 CN claimed
CN-115650948-B Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-12-19 CN claimed
CN-116284713-B Acetylated lactate flame retardant plasticizer containing phosphaphenanthrene group, and preparation method and application thereof 常州大学 2025-05-06 CN disclosed
CN-118742687-A Method for controlling the content of volatile fatty acids in pulp 索理思科技开曼公司 2024-10-01 CN disclosed
CN-118452168-A Hexagon essence and preparation method and application thereof 上海熙美源实业有限公司 2024-08-09 CN disclosed
CN-115745946-B Low-temperature preparation method of glycolide and lactide 中国科学院长春应用化学研究所 2024-03-26 CN disclosed
CN-115650948-B Preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-12-19 CN disclosed
CN-116284713-A Acetylated lactate flame retardant plasticizer containing phosphaphenanthrene group, and preparation method and application thereof 常州大学 2023-06-23 CN disclosed
US-20230159581-A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS SYNOVO GMBH (DE) 2023-05-25 US disclosed
US-20230131943-A1 ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS BURNET MICHEAL W (DE) 2023-04-27 US disclosed
CN-115745946-A Low-temperature preparation method of glycolide-lactide 中国科学院长春应用化学研究所 2023-03-07 CN disclosed
US-11420995-B2 Anti-infective and anti-inflammatory compounds SYNOVO GMBH (DE) 2022-08-23 US disclosed
WO-2021195126-A1 ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS BURNET MICHAEL W (DE) 2021-09-30 WO disclosed
US-20200262857-A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS SYNOVO GMBH (DE) 2020-08-20 US disclosed
WO-2018161039-A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS SYNOVO GMBH (DE) 2018-09-07 WO disclosed
EP-1899274-A1 USE OF SULPHATE-REDUCING THERMOPHILIC ARCHAEA FOR CARRYING OUT A HYDROCARBON DEGRADATION PROCESS Institut de Recherche pour le Développement ( IRD) (FR) 2008-03-19 EP disclosed
WO-2007003779-A1 USE OF SULPHATE-REDUCING THERMOPHILIC ARCHAEA FOR CARRYING OUT A HYDROCARBON DEGRADATION PROCESS INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD) (FR) 2007-01-11 WO disclosed
CN-1201447-A Butyrate prodrugs of lactic acid VERTEX PHARMA (US) 1998-12-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230131943-A1 ANTI-INFECTIVE AND ANTI-VIRAL COMPOUNDS AND COMPOSITIONS CTSA, GAA, SLC7A5 ALDH1A1 3317/4885LMNA 4327/4885HDAC1 366/4885
US-20230159581-A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS CTSA, ALOX15, ALOX5 ALDH1A1 947/4885LMNA 4335/4885HDAC1 378/4885
US-11420995-B2 Anti-infective and anti-inflammatory compounds CTSA, ALOX15, ALOX12 ALDH1A1 911/4885LMNA 3969/4885HDAC1 489/4885
US-20200262857-A1 NOVEL ANTI-INFECTIVE AND ANTI-INFLAMMATORY COMPOUNDS CTSA, ALOX15, ALOX5 ALDH1A1 947/4885LMNA 4335/4885HDAC1 378/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.