Sugi Predict

Sugi Predict / Compounds / SCHEMBL9323973

SCHEMBL9323973

SCHEMBL9323973

COCn1cnc(Cl)c1CCCCl

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 1/20 0.35
▸ CSNK2A2 P19784 1/20 0.32
▸ CSNK2B P67870 1/20 0.32
▸ CSNK2A1 P68400 1/20 0.32
▸ CSNK2A3 Q8NEV1 1/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31332999 0.84 MAPT (0.37) MAPTNPSR1
SCHEMBL31332965 0.79 MAPT (0.36) MAPTNPSR1
SCHEMBL9324883 0.74 MAPT (0.51) MAPTNPSR1
SCHEMBL31332874 0.70 MEN1 (0.33) —
SCHEMBL31332813 0.63 NPSR1 (0.35) MAPTNPSR1
SCHEMBL11723304 0.63 FDPS (0.51) —
SCHEMBL31332871 0.63 MEN1 (0.33) —
SCHEMBL18832304 0.62 P2RX7 (0.48) —
SCHEMBL23657286 0.62 MAPT (0.58) MAPTNPSR1
SCHEMBL9265326 0.61 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0365030-B1 Imidazole compound and process for preparing the same ISHIHARA SANGYO KAISHA (JP) 1994-01-26 — — EP disclosed
US-5023336-A Fungicides, biocides ISHIHARA SANGYO KAISHA LTD. (JP) 1991-06-11 — — US disclosed
EP-0365030-A1 Imidazole compound and process for preparing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1990-04-25 — — EP disclosed