Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11449928 | 0.83 | HTR2A (0.53) | HTR2AHTR2BHTR2CSLC6A4SLC6A2 | |
| SCHEMBL10297511 | 0.79 | HTR2A (0.47) | HTR2AHTR2BHTR2CSLC6A4SLC6A2 | |
| SCHEMBL28975159 | 0.77 | HTR2A (0.46) | HTR2AHTR2BHTR2CSLC6A4SLC6A2 | |
| SCHEMBL6549986 | 0.77 | PPARG (0.53) | KDM4EALDH1A1GAAATML3MBTL1 | |
| SCHEMBL17074475 | 0.77 | HTR2A (0.46) | HTR2AHTR2BHTR2CSLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL6548048 | 0.76 | PPARG (0.52) | KDM4EALDH1A1GAAATML3MBTL1 | |
| SCHEMBL6548042 | 0.76 | ALDH1A1 (0.46) | SLC6A4SLC6A2SLC6A3KDM4EALDH1A1 | |
| SCHEMBL9325345 | 0.75 | MAOA (0.59) | HTR2AHTR2BHTR2CSLC6A4SLC6A2 | |
| SCHEMBL18680739 | 0.75 | ALDH1A1 (0.54) | HTR2AHTR2BHTR2CSLC6A4SLC6A2 | |
| SCHEMBL11296841 | 0.74 | MAOA (0.47) | SLC6A4SLC6A2SLC6A3KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273328-B1 | Triazine derivatives and herbicides containing said derivatives | IDEMITSU KOSAN CO (JP) | 1994-03-09 | — | — | EP | disclosed |
| US-4844731-A | HERBICIDES FOR RICE PADDYS | IDEMITSU COMPANY CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0273328-A2 | Triazine derivatives and herbicides containing said derivatives | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-07-06 | — | — | EP | disclosed |