Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081702 | 0.83 | MAOA (0.44) | MAOAMAOBSLC6A4ALDH1A1L3MBTL1 | |
| SCHEMBL7975248 | 0.80 | SLC6A4 (0.39) | MAOAMAOBSLC6A4ALDH1A1L3MBTL1 | |
| SCHEMBL5174689 | 0.76 | ALDH1A1 (0.42) | MAOAMAOBSLC6A4ALDH1A1L3MBTL1 | |
| SCHEMBL6845929 | 0.76 | ALDH1A1 (0.42) | MAOAMAOBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL1453904 | 0.74 | L3MBTL1 (0.45) | MAOAMAOBSLC6A4ALDH1A1L3MBTL1 | |
| SCHEMBL29066508 | 0.74 | LMNA (0.43) | MAOAMAOBALDH1A1L3MBTL1KDM4E | |
| SCHEMBL9325352 | 0.74 | HTR2A (0.50) | SLC6A4ALDH1A1L3MBTL1KDM4EGAA | |
| SCHEMBL23331965 | 0.73 | MAOA (0.52) | MAOAMAOBSLC6A4ALDH1A1L3MBTL1 | |
| SCHEMBL7362590 | 0.73 | MAOA (0.52) | MAOAMAOBSLC6A4ALDH1A1L3MBTL1 | |
| SCHEMBL3688482 | 0.73 | ALDH1A1 (0.40) | MAOAMAOBALDH1A1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0053015-A1 | 1-Phenylthio-2-aminopropane derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1982-06-02 | — | — | EP | disclosed |