Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 5/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.47 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1171603 | 0.84 | TRPA1 (0.57) | TRPA1TAAR1RIPK1AOC3CACNA1F | |
| SCHEMBL56346 | 0.84 | TAAR1 (0.43) | TRPA1TAAR1RIPK1AOC3CACNA1F | |
| SCHEMBL19664358 | 0.84 | TAAR1 (0.43) | TRPA1TAAR1RIPK1AOC3CACNA1F | |
| SCHEMBL3672929 | 0.83 | TRPA1 (0.67) | TRPA1TAAR1RIPK1AOC3CACNA1F | |
| SCHEMBL9172184 | 0.80 | TRPA1 (0.59) | TRPA1TAAR1RIPK1AOC3CHRM2 | |
| SCHEMBL9233371 | 0.80 | TAAR1 (0.56) | TRPA1TAAR1RIPK1AOC3KDM4E | |
| SCHEMBL508412 | 0.78 | TRPA1 (0.61) | TRPA1TAAR1RIPK1AOC3CACNA1F | |
| SCHEMBL9579271 | 0.78 | TRPA1 (0.61) | TRPA1TAAR1RIPK1AOC3CACNA1F | |
| SCHEMBL5572359 | 0.78 | HTR2A (0.46) | TAAR1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL3864354 | 0.78 | TRPA1 (0.61) | TRPA1TAAR1RIPK1AOC3CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5362481-A | Useful in cosmetics and dermatology | 3V INC. (US) | 1994-11-08 | — | — | US | disclosed |