Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19664358 | 0.86 | TAAR1 (0.43) | TAAR1TRPA1RIPK1LMNACACNA1F | |
| SCHEMBL9325717 | 0.84 | TRPA1 (0.55) | TAAR1TRPA1RIPK1ALDH1A1CACNA1F | |
| SCHEMBL15463452 | 0.84 | POLB (0.44) | TAAR1RIPK1ALDH1A1LMNACHRM2 | |
| SCHEMBL5572359 | 0.80 | HTR2A (0.46) | TAAR1CACNA1FCHRM2CHRM1ADRA2B | |
| SCHEMBL23795865 | 0.77 | TAAR1 (0.47) | TAAR1TRPA1ALDH1A1LMNACACNA1F | |
| SCHEMBL3225501 | 0.77 | CACNA1B (0.37) | TRPA1AOC3 | |
| SCHEMBL7941668 | 0.77 | TAAR1 (0.42) | TAAR1TRPA1ALDH1A1LMNACACNA1F | |
| SCHEMBL9493121 | 0.77 | HRH1 (0.54) | TAAR1TRPA1ALDH1A1LMNACACNA1F | |
| SCHEMBL8015411 | 0.76 | TAAR1 (0.39) | TAAR1TRPA1ALDH1A1LMNACACNA1F | |
| SCHEMBL9579271 | 0.75 | TRPA1 (0.61) | TAAR1TRPA1RIPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107141241-A | Copper-sulphide ores flotation collector and its preparation method and application | 九江学院 | 2017-09-08 | — | — | CN | claimed |
| US-20090233920-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-17 | — | — | US | claimed |
| EP-1968940-A1 | 3 , 5-SUBSTITUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS | Novartis AG (CH) | 2008-09-17 | — | — | EP | claimed |
| EP-1907359-A2 | 3,5-SUBSTITUTED PIPERIDINE DERIVATIVES EFFECTIVE ON RENIN-RELATED DISORDERS | Novartis AG (CH) | 2008-04-09 | — | — | EP | claimed |
| WO-2007077005-A1 | 3 , 5-SUBSTITΓUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2007-07-12 | — | — | WO | claimed |
| WO-2007006534-A2 | PIPERIDINE DERIVATIVES USEFUL IN THE DIAGNOSTIC AND THERAPEUTIC TREATMENT OF DISEASES DEPENDING ON RENIN ACTIVITY | NOVARTIS AG (CH) | 2007-01-18 | — | — | WO | claimed |
| CN-1042226-C | Heterocyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-02-24 | — | — | CN | claimed |
| CN-110437046-B | Fluorine atom-containing polymer and field of use thereof | 日产化学工业株式会社 | 2022-08-16 | — | — | CN | disclosed |
| CN-107406584-B | Fluorine atom-containing polymer and field of use thereof | 日产化学工业株式会社 | 2020-06-09 | — | — | CN | disclosed |
| CN-110437046-A | Polymer containing fluorine atom and its utilize technical field | NISSAN CHEMICAL IND LTD | 2019-11-12 | — | — | CN | disclosed |
| CN-106362869-B | The application of one kind 1,2,4- triazole -3- thiones flotation collectors | 中南大学 | 2018-10-09 | — | — | CN | disclosed |
| US-20180030200-A1 | FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-02-01 | — | — | US | disclosed |
| EP-3263622-A1 | FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME | Nissan Chemical Industries, Ltd. (JP) | 2018-01-03 | — | — | EP | disclosed |
| US-5212320-A | Enzyme inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-05-18 | — | — | US | disclosed |
| WO-1993003012-A1 | INDOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-18 | — | — | WO | disclosed |
| EP-0458207-A2 | Indole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-27 | — | — | EP | disclosed |
| EP-0425134-A1 | Condensed pyrrolo derivatives, process for their preparation and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| CN-1030415-A | Saturated heterocycle carboxamide derivatives and its preparation method | YAMANOUCHI PHARMA CO LTD (JP) | 1989-01-18 | — | — | CN | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090233920-A1 | ORGANIC COMPOUNDS | REN, ACE, AGTR1 | TAAR1 199/4885TRPA1 392/4885RIPK1 4447/4885 |
| US-20180030200-A1 | FLUORINE ATOM-CONTAINING POLYMER AND USE OF SAME | AFF2, AFF1, AFF4 | TAAR1 2400/4885TRPA1 3711/4885RIPK1 4415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.