SCHEMBL9325874

SCHEMBL9325874

O=c1c(Cl)cc2nc3cc(Cl)cc(Cl)c3oc-2c1Cl

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 2/20 0.34
USP2 O75604 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
ALOX12 P18054 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HSD17B10 Q99714 1/20 0.34
AKR1B1 P15121 2/20 0.34
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
CSNK2A3 Q8NEV1 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
AHR P35869 2/20 0.32
PTPN1 P18031 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19127003 0.79 MEN1 (0.35) AHRMAPT
SCHEMBL28661441 0.72 PSMB8 (0.44) POLBAHRMAPT
SCHEMBL10680532 0.70 HPGD (0.41) GPR35USP2POLBHPGDALOX15
SCHEMBL22561684 0.70 ALOX15 (0.52) GPR35USP2POLBHPGDALOX15
SCHEMBL10727909 0.69 AHR (0.38) GPR35USP2POLBHPGDALOX15
SCHEMBL9836825 0.67 AKR1B1 (0.39) GPR35USP2POLBHPGDALOX15
SCHEMBL6010774 0.66 AHR (0.36) GPR35USP2POLBHPGDALOX15
SCHEMBL11593571 0.66 KCNA3 (0.37) GPR35USP2POLBHPGDALOX15
SCHEMBL646762 0.66 AHR (0.36) GPR35USP2POLBHPGDALOX15
SCHEMBL30612624 0.64 AKR1B1 (0.43) GPR35USP2POLBHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5336600-A Incubating samples with fluorescent reagent which has observable decrease in emitted light in presence of microorganisms, kits for screening blood, urine, foods, water drugs or cosmetics BIO MERIEUX (FR) 1994-08-09 US claimed