Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.35 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | F12 | P00748 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819961 | 0.82 | GAA (0.43) | HPGDPOLBALOX15ALOX12HSD17B10 | |
| SCHEMBL10680532 | 0.81 | HPGD (0.41) | AKR1B1HPGDUSP2POLBALOX15 | |
| SCHEMBL9820082 | 0.75 | MCL1 (0.35) | HPGDUSP2POLBHSD17B10MAPT | |
| SCHEMBL9819945 | 0.74 | MEN1 (0.41) | HPGDPOLBHSD17B10MAPTKDM4E | |
| SCHEMBL9819998 | 0.72 | GAA (0.44) | HPGDPOLBHSD17B10MAPTKDM4E | |
| SCHEMBL9820046 | 0.72 | GRIN1 (0.36) | AKR1B1HPGDUSP2POLBALOX15 | |
| SCHEMBL9835193 | 0.71 | GAA (0.45) | HPGDPOLBALOX15HSD17B10MAPT | |
| SCHEMBL9325874 | 0.67 | GPR35 (0.34) | AKR1B1HPGDUSP2POLBALOX15 | |
| SCHEMBL9819993 | 0.64 | — | — | |
| SCHEMBL10447737 | 0.64 | CA1 (0.43) | HPGDCASP1HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0210559-B1 | N-ACYLDIHYDRORESORUFIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AS WELL AS THEIR USE FOR THE DETERMINATION OF HYDROGEN PEROXIDE, PEROXIDATICALLY ACTIVE COMPOUNDS, OR PEROXIDASE | Roche Diagnostics GmbH (DE) | 1991-09-25 | — | — | EP | disclosed |
| EP-0210559-A2 | N-Acyldihydroresorufin derivatives, process for their preparation as well as their use for the determination of hydrogen peroxide, peroxidatically active compounds, or peroxidase | Roche Diagnostics GmbH (DE) | 1987-02-04 | — | — | EP | disclosed |