Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.74 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MYOC | Q99972 | 1/20 | 0.51 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23142534 | 0.91 | LMNA (0.71) | HTTHSPB1LMNARAB9AMEN1 | |
| SCHEMBL1087188 | 0.87 | HTT (0.73) | HTTHSPB1LMNARAB9AMEN1 | |
| SCHEMBL10827290 | 0.86 | HTT (1.00) | HTTHSPB1LMNARAB9AMEN1 | |
| SCHEMBL2011179 | 0.84 | HSPB1 (0.79) | HTTHSPB1LMNARAB9AMEN1 | |
| SCHEMBL9183872 | 0.84 | HSPB1 (0.79) | HTTHSPB1LMNARAB9AMEN1 | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 | 0.84 | HSPB1 (0.79) | HTTHSPB1LMNARAB9AMEN1 | |
| SCHEMBL11689190 | 0.84 | HSPB1 (0.79) | HTTHSPB1LMNARAB9AMEN1 | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL8934595 | 0.82 | HSPB1 (0.76) | HTTHSPB1LMNARAB9AMEN1 | |
| SCHEMBL3208134 | 0.78 | HSPB1 (0.70) | HTTHSPB1LMNARAB9AMEN1 | |
| SCHEMBL311582 | 0.78 | KMT2A (0.73) | HTTHSPB1LMNARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111039964-A | Tetrahedral cage-like structure complex and preparation method thereof | 南京工业大学 | 2020-04-21 | — | — | CN | disclosed |
| EP-0303108-B1 | Light-sensitive composition, registration material prepared therefrom and process for the production of negative relief images | HOECHST AG (DE) | 1994-02-23 | — | — | EP | disclosed |
| US-5102929-A | Molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-07 | — | — | US | disclosed |
| EP-0451359-A1 | Blends of polyarylenesulphides, glassfibres and nitroaryloxyheterocyclics | BAYER AG (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-4990429-A | Process for the production of negative relief copies utilizing reversal processing | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-05 | — | — | US | disclosed |
| US-4889788-A | Photosensitive composition, photosensitive copying material prepared from this composition with thermal hardening symmetric triazine alkyl(aryl)-ether | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-12-26 | — | — | US | disclosed |
| EP-0303108-A2 | Light-sensitive composition, registration material prepared therefrom and process for the production of negative relief images | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-02-15 | — | — | EP | disclosed |