Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029858 | 0.85 | LTA4H (0.50) | PTGESLTA4HPPARGPPARAFDFT1 | |
| SCHEMBL7528135 | 0.84 | FFAR1 (0.56) | PTGESPPARGPPARAFFAR1 | |
| SCHEMBL11236263 | 0.81 | MMP13 (0.46) | LTA4HPPARGPPARAFDFT1FFAR1 | |
| SCHEMBL7528693 | 0.79 | FFAR1 (0.50) | LTA4HPPARGPPARAFFAR1NPC1 | |
| SCHEMBL9848779 | 0.79 | FFAR1 (0.41) | PTGESLTA4HNR1H2BAXPPARG | |
| SCHEMBL7524365 | 0.78 | NPC1 (0.46) | LTA4HNR1H2BAXFFAR1NPC1 | |
| SCHEMBL10853331 | 0.78 | PPARG (0.41) | LTA4HPPARGPPARACETP | |
| SCHEMBL9324651 | 0.73 | FDFT1 (0.47) | LTA4HNR1H2BAXFDFT1FFAR1 | |
| SCHEMBL3633492 | 0.73 | CETP (0.51) | LTA4HPPARGPPARAMMEACE | |
| SCHEMBL9339511 | 0.73 | FFAR1 (0.46) | PTGESFFAR1TSHRHSD17B10CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0393513-B1 | Preparation of a difluorohalomethoxybenzene | MITSUI TOATSU CHEMICALS (JP) | 1994-03-09 | — | — | EP | claimed |