Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CETP | P11597 | 3/20 | 0.37 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029858 | 0.81 | LTA4H (0.50) | SMN1; SMN2HTTKDM4EALDH1A1FFAR1 | |
| SCHEMBL9326504 | 0.81 | PTGES (0.42) | FFAR1CETPFDFT1LTA4HPPARG | |
| SCHEMBL10483784 | 0.78 | MMP13 (0.48) | MMP13SMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL7528135 | 0.77 | FFAR1 (0.56) | SMN1; SMN2ALDH1A1FFAR1PPARGPPARA | |
| SCHEMBL10853331 | 0.76 | PPARG (0.41) | SMN1; SMN2HTTKDM4EALDH1A1CETP | |
| SCHEMBL7528693 | 0.75 | FFAR1 (0.50) | SMN1; SMN2ALDH1A1FFAR1CETPLTA4H | |
| SCHEMBL10544640 | 0.75 | MMP13 (0.47) | MMP13SMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL13718948 | 0.73 | FFAR1 (0.48) | MMP13SMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL13718930 | 0.73 | TAAR1 (0.60) | SMN1; SMN2HTTKDM4EALDH1A1TAAR1 | |
| SCHEMBL11236257 | 0.73 | MMP13 (0.48) | MMP13SMN1; SMN2HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57072928-A | — | — | None | — | — | JP | disclosed |
| JP-S5772928-A | NOVEL 2-ARYLPROPYL ETHER DERIVTIVE AND THIOETHER DERVIATIVE, THEIR PREPARATIONS, INSECTICIDE, AND ACARICIDE | MITSUI TOATSU CHEM INC | 1982-05-07 | — | — | JP | disclosed |