Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 9/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533598 | 0.89 | HPGD (0.58) | HPGDPPARGGPR35PTPN1POLB | |
| SCHEMBL9534304 | 0.89 | HPGD (0.58) | HPGDPPARGGPR35PTPN1POLB | |
| SCHEMBL9326985 | 0.81 | CSNK2A2 (0.62) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9327176 | 0.81 | PPARG (0.64) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9122231 | 0.80 | CSNK2A2 (0.50) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9536414 | 0.79 | KMT2A (0.45) | HPGD | |
| SCHEMBL9536311 | 0.77 | HPGD (0.49) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9535405 | 0.75 | PPARG (0.58) | PPARG | |
| SCHEMBL9433166 | 0.75 | HPGD (0.75) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A | |
| SCHEMBL9124681 | 0.74 | HPGD (0.53) | CSNK2A2CLK1CSNK2BCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | claimed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | claimed |
| EP-0555251-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP plc (GB) | 1993-08-18 | — | — | EP | disclosed |
| WO-1992007838-A1 | THIAZOLIDINE DIONE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1992-05-14 | — | — | WO | disclosed |